1-Course Objectives:
• Identify chiral molecules and use the (R)-(S) nomenclature correctly.
• Describe and explain conformational analysis in alkanes and cycloalkanes.
• Explain the mechanism of free radical chlorination.
2- Course conents:
-Stereochemistry and stereoisomerism Isomer number and tetrahedral carbon.
-Optical activity,plane-polarized light, the polarimeter and specific rotation.
-Enantiomerism.Chirality.Enantiomers.The racemic modification
-Specification of configuration: R and S. Sequence rules.
-Diastereomers. Meso structure
-Specification of configuration: more than one chiral center. Conformational isomers
-Stereoisomerism, Reactions involving stereoisomers, Generation of a chiral center. Synthesis and optical activity, Reactions of chiral molecules. Bond breaking, Reactions of chiral molecules. Relating configurations, Optical purity, Reactions of chiral molecules. Generation of a second chiral center. Formation of enantiomers and diastereomers. Reactions of chiral molecules with optically active reagents. Resolution. Reactions of chiral molecules. Mechanism of free-radical chlorination. Stereoselective and stereospecific reactions. Syn- and anti-Addition. Mechanism of halogen addition
Stereochemistry of some compounds (Nitrogen, Sulphur phosphorus and Arsenic compounds).