توصيف مقرر دراسي
1- بيانات المقرر
الرمز الكودي:
ZOOL 417 اسم المقرر:
Toxicology and Environmental Pollution المستوى:
الرابع
التخصص:
-Zoology (Single)
-Zoology (Major)
عدد الوحدات الدراسية: 2 ساعات معتمدة نظري 2 عملي 0
إجمالي الساعات: 2 ساعات اسبوعيا
Program: Bachelor of Science
Major or minor element of program: Zoology
Department offering the program: Zoology Department
Department offering the course: Zoology Department
Level: 4th Semester:1st
2- هدف المقرر Aims By the end of this course, the student should be able to demonstrate abundant and competent knowledge of contemporary concepts in the: principles of toxicology - classes of toxicants - routes of exposure - toxicant processing in vivo - toxic action - organ toxicity - forensic and clinical toxicology - environmental toxicology - toxicity tests - mechanisms of toxicity - detoxification and biotransformation - free radicals and detoxification.
3- المستهدف من تدريس المقرر: Intended Learning Outcomes
أ- المعلومات والمفاهيم
Knowledge and Understanding Upon successful completing of this course, the student should be able to:
1- Define the term of toxicology with a brief history of toxicology, sources of toxic compounds and movement of toxicants in the environment.
2- Identify the classes of toxicants.
3- Explain the routes of exposure to toxicants.
4- Describe the toxicant processing in vivo.
5- Illustrate the acute and chronic toxicity, chemical carcinogenesis, mutagenesis and teratogenesis.
6- Describe the events that occur in organ toxicity including hepatotoxicity, nephrotoxicity, toxicology of the nervous system, reproductive system, endocrine toxicology and respiratory toxicology.
7- Explain the forensic and clinical toxicology.
8- Describe the basics of environmental toxicology, transport and fate of toxicants in the environment and environmental risk assessment.
9- Describe the toxicity tests, mechanisms of toxicity, detoxication, and biotransformation.
ب- المهارات الذهنية
Intellectual
Skills 1- Analyse mechanisms of transport across the cell membranes
2- Analyse case studies and suggest possible impairments in acute and chronic toxicity.
3- Formulate points of interactions and overlap between chemical carcinogenesis, mutagenesis and teratogenesis
4- Predict chemical and physiological effects on xenobiotic metabolism
5- Criticize factors that influence bioaccumulation of toxicants.
6- Predict the effect of different types organ toxicity.
جـ- المهارات المهنية الخاصة بالمقرر
Professional Skills 1- Write short essays on interesting issues and latest advances relevant to the topics covered in this course.
2- Locate and download online information independently.
د -المهارات العامــــــة
General Skills This course helps the student in his future career to properly interaction with his colleagues of other faculty of science departments and even those of other faculties e.g. agriculture-medicine.
1- محتوى المقــــــرر Course Content
Topics
Lecture hours Practical hours Total No. of hours
1- PRINCIPLES OF TOXICOLOGY
2- CLASSES OF TOXICANTS
a- Water and Soil Pollutants
b- Air Pollutants
c- Occupational Toxicants
d- Metals
e- Treatment of Metal Poisoning
f- Agricultural Chemicals
g- Food Additives and Contaminants
h- Natural Toxins
i- Radioactive materials
j- Solvents
k- Therapeutic Drugs
l- Drugs of Abuse
m- Combustion Product
n- Cosmetics
3- ROUTES OF EXPOSURE
4- TOXICANT PROCESSING IN VIVO
a- Absorption and Distribution of Toxicants
b- Duration and frequency of exposure
c- Metabolism of Toxicants
d- Reactive Metabolites
e- Tolerance and Species differences
f- Chemical and Physiological Effects on Xenobiotic Metabolism
g- Elimination of Toxicants
5- TOXIC ACTION
a- Acute and chronic Toxicity
b- Chemical Carcinogenesis and Mutagenesis
c- Teratogenesis
6- ORGAN TOXICITY
a- Hepatotoxicity
b- Nephrotoxicity
c- Toxicology of the Nervous System
d- Endocrine Toxicology
e- Respiratory Toxicology
f- Reproductive System
g- Immune System
7- FORENSIC AND CLINICAL TOXICOLOGY
8- ENVIRONMENTAL TOXICOLOGY
a- Toxicant Analysis: Analytical Methods and Quality Assurance
b- Basics of Environmental Toxicology
c- Transport and Fate of Toxicants in the Environment
d- Environmental Risk Assessment
9- TOXICITY TESTS
10- MECHANISMS OF TOXICITY
11- DETOXICATION AND BIOTRANSFORMATION
12- FREE RADICALS AND DETOXIFICATION
13- Review activity and feedback discussion
2- أساليب التعليم والتعلم
Teaching and Learning Methods 1- Lectures using an overhead projector with colour transparencies along with the blackboard.
2- PowerPoint presentations and movies with English-native voice.
3- Classroom discussions.
4- Submission of written essays and reports.
5- Oral presentations
6- أساليب التعليم والتعلم للطلاب ذوى القدرات المحدودة
Teaching and Learning Methods of Disables Not available
7- تقويم الطــــــــلاب
Students Assessment
أ- الأساليب المستخدمة
Tools 1- Oral examination to assess skills of discussions and presenting information systematically.
2- Written examination to assess the student's ability to demonstrate his understanding of the major concepts covered in this course from an integrated point of view.
3- Short essays and reports submitted or presented orally by the student.
ب- التوقيت
Time Schedule Time is determined by the faculty examination schedule.
جـ- توزيع الدرجات
Grading System (In accordance with the Faculty bylaws)
Student activity, quizzes and Mid-Term 25.0 %
Final-Term Written Exam 70.0 %
Oral Exam 5.0 %
Practical Exam 0.0 %
Total 100 %
8- قائمة الكتب الدراسية والمراجع
List of References
أ- مذكرات
Course Note Course notebooks and hand-outs prepared by the course instructors.
ب- كتب ملزمة
Required Books (Text Books) --------
جـ- كتب مقترحة
Recommended Books 1. T.C. Vandivort and D.L. Eaton (2014). Principles of Toxicology. University of Washington, Seattle, WA, USA.
2. H. M. Bolt, F. A. de Wolff and P. Th. Henderson (1992). Medical Toxicology. Springer-Verlag.
3. Derelanko, M.J. and Hollinger, M. A. (2002). Handbook of Toxicology, Second edition. Talyor and Francis.
د- دوريات علمية أو نشرات ... إلخ
Periodicals, web sites…etc.
Some recent international publications for the course instructors in the field of Toxicology.
أستاذ المادة: أ.د. وائل السيد
1- بيانات المقرر
الرمز الكودي:
ZOOL 417 اسم المقرر:
Toxicology and Environmental Pollution المستوى:
الرابع
التخصص:
-Zoology (Single)
-Zoology (Major)
عدد الوحدات الدراسية: 2 ساعات معتمدة نظري 2 عملي 0
إجمالي الساعات: 2 ساعات اسبوعيا
Program: Bachelor of Science
Major or minor element of program: Zoology
Department offering the program: Zoology Department
Department offering the course: Zoology Department
Level: 4th Semester:1st
2- هدف المقرر Aims By the end of this course, the student should be able to demonstrate abundant and competent knowledge of contemporary concepts in the: principles of toxicology - classes of toxicants - routes of exposure - toxicant processing in vivo - toxic action - organ toxicity - forensic and clinical toxicology - environmental toxicology - toxicity tests - mechanisms of toxicity - detoxification and biotransformation - free radicals and detoxification.
3- المستهدف من تدريس المقرر: Intended Learning Outcomes
أ- المعلومات والمفاهيم
Knowledge and Understanding Upon successful completing of this course, the student should be able to:
1- Define the term of toxicology with a brief history of toxicology, sources of toxic compounds and movement of toxicants in the environment.
2- Identify the classes of toxicants.
3- Explain the routes of exposure to toxicants.
4- Describe the toxicant processing in vivo.
5- Illustrate the acute and chronic toxicity, chemical carcinogenesis, mutagenesis and teratogenesis.
6- Describe the events that occur in organ toxicity including hepatotoxicity, nephrotoxicity, toxicology of the nervous system, reproductive system, endocrine toxicology and respiratory toxicology.
7- Explain the forensic and clinical toxicology.
8- Describe the basics of environmental toxicology, transport and fate of toxicants in the environment and environmental risk assessment.
9- Describe the toxicity tests, mechanisms of toxicity, detoxication, and biotransformation.
ب- المهارات الذهنية
Intellectual
Skills 1- Analyse mechanisms of transport across the cell membranes
2- Analyse case studies and suggest possible impairments in acute and chronic toxicity.
3- Formulate points of interactions and overlap between chemical carcinogenesis, mutagenesis and teratogenesis
4- Predict chemical and physiological effects on xenobiotic metabolism
5- Criticize factors that influence bioaccumulation of toxicants.
6- Predict the effect of different types organ toxicity.
جـ- المهارات المهنية الخاصة بالمقرر
Professional Skills 1- Write short essays on interesting issues and latest advances relevant to the topics covered in this course.
2- Locate and download online information independently.
د -المهارات العامــــــة
General Skills This course helps the student in his future career to properly interaction with his colleagues of other faculty of science departments and even those of other faculties e.g. agriculture-medicine.
1- محتوى المقــــــرر Course Content
Topics
Lecture hours Practical hours Total No. of hours
1- PRINCIPLES OF TOXICOLOGY
2- CLASSES OF TOXICANTS
a- Water and Soil Pollutants
b- Air Pollutants
c- Occupational Toxicants
d- Metals
e- Treatment of Metal Poisoning
f- Agricultural Chemicals
g- Food Additives and Contaminants
h- Natural Toxins
i- Radioactive materials
j- Solvents
k- Therapeutic Drugs
l- Drugs of Abuse
m- Combustion Product
n- Cosmetics
3- ROUTES OF EXPOSURE
4- TOXICANT PROCESSING IN VIVO
a- Absorption and Distribution of Toxicants
b- Duration and frequency of exposure
c- Metabolism of Toxicants
d- Reactive Metabolites
e- Tolerance and Species differences
f- Chemical and Physiological Effects on Xenobiotic Metabolism
g- Elimination of Toxicants
5- TOXIC ACTION
a- Acute and chronic Toxicity
b- Chemical Carcinogenesis and Mutagenesis
c- Teratogenesis
6- ORGAN TOXICITY
a- Hepatotoxicity
b- Nephrotoxicity
c- Toxicology of the Nervous System
d- Endocrine Toxicology
e- Respiratory Toxicology
f- Reproductive System
g- Immune System
7- FORENSIC AND CLINICAL TOXICOLOGY
8- ENVIRONMENTAL TOXICOLOGY
a- Toxicant Analysis: Analytical Methods and Quality Assurance
b- Basics of Environmental Toxicology
c- Transport and Fate of Toxicants in the Environment
d- Environmental Risk Assessment
9- TOXICITY TESTS
10- MECHANISMS OF TOXICITY
11- DETOXICATION AND BIOTRANSFORMATION
12- FREE RADICALS AND DETOXIFICATION
13- Review activity and feedback discussion
2- أساليب التعليم والتعلم
Teaching and Learning Methods 1- Lectures using an overhead projector with colour transparencies along with the blackboard.
2- PowerPoint presentations and movies with English-native voice.
3- Classroom discussions.
4- Submission of written essays and reports.
5- Oral presentations
6- أساليب التعليم والتعلم للطلاب ذوى القدرات المحدودة
Teaching and Learning Methods of Disables Not available
7- تقويم الطــــــــلاب
Students Assessment
أ- الأساليب المستخدمة
Tools 1- Oral examination to assess skills of discussions and presenting information systematically.
2- Written examination to assess the student's ability to demonstrate his understanding of the major concepts covered in this course from an integrated point of view.
3- Short essays and reports submitted or presented orally by the student.
ب- التوقيت
Time Schedule Time is determined by the faculty examination schedule.
جـ- توزيع الدرجات
Grading System (In accordance with the Faculty bylaws)
Student activity, quizzes and Mid-Term 25.0 %
Final-Term Written Exam 70.0 %
Oral Exam 5.0 %
Practical Exam 0.0 %
Total 100 %
8- قائمة الكتب الدراسية والمراجع
List of References
أ- مذكرات
Course Note Course notebooks and hand-outs prepared by the course instructors.
ب- كتب ملزمة
Required Books (Text Books) --------
جـ- كتب مقترحة
Recommended Books 1. T.C. Vandivort and D.L. Eaton (2014). Principles of Toxicology. University of Washington, Seattle, WA, USA.
2. H. M. Bolt, F. A. de Wolff and P. Th. Henderson (1992). Medical Toxicology. Springer-Verlag.
3. Derelanko, M.J. and Hollinger, M. A. (2002). Handbook of Toxicology, Second edition. Talyor and Francis.
د- دوريات علمية أو نشرات ... إلخ
Periodicals, web sites…etc.
Some recent international publications for the course instructors in the field of Toxicology.
أستاذ المادة: أ.د. وائل السيد
